FITC标记的DMRTA2蛋白抗体
产品名称： FITC标记的DMRTA2蛋白抗体
英文名称： Anti-DMRTA2/FITC
产品编号： HZ-14348R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-DMRTA2/FITC Conjugated antibody
FITC标记的DMRTA2蛋白抗体
| 英文名称 | Anti-DMRTA2/FITC |
| 中文名称 | FITC标记的DMRTA2蛋白抗体 |
| 别 名 | DMRT A2; DMRT like family A2; DMRT5; DMRTA 2; dmrta2; DMTA2_HUMAN; Doublesex- and mab-3-related transcription factor 5; Doublesex- and mab-3-related transcription factor A2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 干细胞 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMRTA2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: May be involved in sexual development. Subcellular Location: Nucleus. Tissue Specificity: Expressed in testis. Similarity: Belongs to the DMRT family. Contains 1 DM DNA-binding domain. Database links: Entrez Gene: 63950 Human Entrez Gene: 242620 Mouse Entrez Gene: 313471 Rat SwissProt: Q5TFQ3 Human SwissProt: Q96SC8 Human SwissProt: A2A9A2 Mouse Unigene: 334481 Human Unigene: 32825 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DMRTA2是一个542个氨基酸的蛋白质，定位于细胞核并含有一个DM DNA结合结构域。表达睾丸，DMRTA2被认为是参与成熟过程中的性发育过程。编码DMRTA2的基因定位于人类1号染色体，跨越2.6亿个碱基对，包含3000多个基因，占人类基因组的近8%。染色体1包含许多疾病相关基因，包括那些与家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病、精神分裂症和Usher综合征相关的基因。染色体1异常存在于各种癌症中，包括头颈癌、恶性黑色素瘤和多发性骨髓瘤。