FITC标记的DNA引物酶抗体上海沪震实业有限公司

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产品名称: FITC标记的DNA引物酶抗体
英文名称: Anti-DNA Primase/FITC
抗体货号: HZ-14357R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 9:34:00
详细资料:  实验方法技术资料
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诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-DNA Primase/FITC Conjugated antibody

FITC标记的DNA引物酶抗体

 

英文名称 Anti-DNA Primase/FITC
中文名称 FITC标记的DNA引物酶抗体
别    名 dJ422B11.1.1; DNA primase 58kDa subunit; DNA primase large subunit; DNA primase p58; DNA primase subunit p58; p58; Polypeptide 2A p58; PRIM2; PRIM2A; PRI2_HUMAN; Primase DNA polypeptide 2 (58kDa); Primase polpeptide 2A (58kD); Primase polpeptide 2A 58kDa.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNA Primase
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. [provided by RefSeq, Sep 2013]

Function:
DNA primase synthesizes small ribonucleotide primers for the initiation of DNA replication. The eukaryotic primase is a heterodimer of a small and a large subunit, p49 and p58 respectively. These two subunits purify as a complex tightly bound to DNA polymerase alpha. This tight association implicates polymerase alpha as the lagging-strand DNA polymerase in replication. Uniquely, primases are able to synthesize nucleotides de novo on a template by the formation of an initial dinucleotide. DNA primase initiates synthesis with a triphosphate purine moiety at the 5'-end. After synthesis of 7-10 ribonucleotides, the primer template is translocated intramolecularly to the active site of the DNA polymerase alpha subunit. The p49 subunit of DNA primase contains the catalytic active site. The human primase subunits are 90% identical in amino acid sequence to the mouse homologs.

Subunit:
Heterodimer of a small subunit and a large subunit.

Similarity:
Belongs to the eukaryotic-type primase large subunit family.

Database links:

Entrez Gene: 5558 Human

Entrez Gene: 301323 Rat

GenBank: NP_000938.2 Human

Omim: 176636 Human

SwissProt: P49643 Human

SwissProt: O89044 Rat

Unigene: 654580 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

该基因编码DNA聚合酶的58千道尔顿亚基,该酶在DNA复制中起关键作用。编码的蛋白质形成具有49千道尔顿亚基的异源二聚体。该异二聚体作为DNA导向的RNA聚合酶,用于合成小RNA引物,用于在DNA的滞后链上产生冈崎片段。[ RefSeq,SEP 2013提供]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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