FITC标记的轴丝动力蛋白12抗体上海沪震实业有限公司

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产品名称: FITC标记的轴丝动力蛋白12抗体
英文名称: Anti-DNAH12/FITC
抗体货号: HZ-14361R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 9:35:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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陈先生
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上海·中国-上海
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产品详细描述

 Rabbit Anti-DNAH12/FITC Conjugated antibody

FITC标记的轴丝动力蛋白12抗体

 

英文名称 Anti-DNAH12/FITC
中文名称 FITC标记的轴丝动力蛋白12抗体
别    名 DYH12_HUMAN; Dynein heavy chain 12, axonemal; Axonemal beta dynein heavy chain 12; Axonemal dynein heavy chain 12-like protein; Axonemal dynein heavy chain 12 like protein; Axonemal dynein heavy chain 7-like protein; Ciliary dynein heavy 12; Dynein heavy chain 7-like, axonemal; Axonemal dynein heavy chain 7 like protein; Dynein heavy chain domain-containing protein 2; DHC3; DLP12; DNAH12L; DNAH7L; DNAHC3; DNHD2; HDHC3; HL19.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 357kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH12
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; complexes that transport cellular cargo toward the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH12 is a 3,092 amino acid protein of cilium axoneme that exists as three alternatively spliced isoforms. A member of the dynein heavy chain family, DNAH12L is involved in sperm flagellar assembly and is encoded by a gene located on human chromosome 3.

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly

Subunit:
Consists of at least two heavy chains and a number of intermediate and light chains.

Subcellular Location:
Cytoplasm, cytoskeleton, cilium axoneme.

Similarity:
Belongs to the dynein heavy chain family.

Database links:

Entrez Gene: 201625 Human

SwissProt: Q6ZR08 Human

Unigene: 201378 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

动力蛋白是多亚基、高分子量的ATPase,它与微管相互作用,通过将ATP的化学能转化为运动的机械能来产生力。细胞质或轴丝状动力蛋白重链、中间链、轻链和轻中间链都是负端向马达的组成部分;复合体将细胞货物运输到细胞的中心区域。轴丝动力蛋白马达包含一至三个不相同的重链,在纤毛和鞭毛的轴丝中导致微管滑动,这是纤毛搏动和推动细胞所必需的机制。DNaH12是纤毛轴突的3092个氨基酸蛋白,以三个交替剪接的亚型存在。DNAH12L是强力蛋白重链家族的成员,参与精子鞭毛装配,由位于人类3号染色体上的基因编码。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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