FITC标记的轴丝动力蛋白1抗体上海沪震实业有限公司

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产品名称: FITC标记的轴丝动力蛋白1抗体
英文名称: Anti-DNAH1/FITC
抗体货号: HZ-14359R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 9:37:00
详细资料:  实验方法技术资料
浏览人数:12
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
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上海·中国-上海
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产品详细描述

 Rabbit Anti-DNAH1/FITC Conjugated antibody

FITC标记的轴丝动力蛋白1抗体

 

英文名称 Anti-DNAH1/FITC
中文名称 FITC标记的轴丝动力蛋白1抗体
别    名 axonemal; Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; DNAH1; DNAHC1; DYH1_HUMAN; Dynein heavy chain 1; hDHC7; Heat shock regulated protein 1; Ciliary dynein heavy chain 1; HL 11; HL11; HSRF-1; XLHSRF-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 494kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH1 (dynein heavy chain 1, axonemal), also known as heat shock regulated protein 1 or ciliary dynein heavy chain 1, is a 4,330 amino acid protein consisting of at least two heavy chains and several intermediate and light chains. Mutations in the gene encoding DNAH1 may be a cause of primary ciliary dyskinesia, also known as Kartagener Syndrome, which is characterized by chronic recurrent respiratory infections due to defective cilia action in the respiratory tract. There are three isoforms of DNAH1 that exist as a result of alternative splicing events.

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.

Subcellular Location:
Cytoplasm > cytoskeleton > cilium axoneme.

Tissue Specificity:
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain.

Similarity:
Belongs to the dynein heavy chain family.

Database links:

Entrez Gene: 25981 Human

Omim: 603332 Human

SwissProt: Q9P2D7 Human

Unigene: 655469 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

动力蛋白是多亚基、高分子量的ATPase,它与微管相互作用,通过将ATP的化学能转化为运动的机械能来产生力。轴丝动力蛋白马达包含一至三个不相同的重链,在纤毛和鞭毛的轴丝中导致微管滑动,这是纤毛打动和推动细胞所必需的机制。DNAH1(dynein..1,axonemal)又称热休克调节蛋白1或睫状dynein..1,是由至少两个重链和几个中间和轻链组成的4330个氨基酸蛋白。编码DNAH1的基因突变可能是原发性睫状肌运动障碍的原因之一,也称为卡塔格纳综合征,其特征是呼吸道中的纤毛功能缺陷导致慢性反复呼吸道感染。DNH1的三种异构体存在于选择性剪接事件的结果中。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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