FITC标记的轴丝动力蛋白2抗体
产品名称： FITC标记的轴丝动力蛋白2抗体
英文名称： Anti-DNAH2/FITC
产品编号： HZ-14363R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-DNAH2/FITC Conjugated antibody
FITC标记的轴丝动力蛋白2抗体
| 英文名称 | Anti-DNAH2/FITC |
| 中文名称 | FITC标记的轴丝动力蛋白2抗体 |
| 别 名 | axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dnah2; DYH2_HUMAN; Dynein heavy chain 2; Dynein heavy chain domain-containing protein 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 507kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAH2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008] Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Subcellular Location: Cytoplasm; cytoskeleton; cilium axoneme. Tissue Specificity: Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung. Similarity: Belongs to the dynein heavy chain family. Contains 5 TPR repeats. Database links: Entrez Gene: 146754 Human SwissProt: Q9P225 Human Unigene: 367649 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
动力蛋白是由几个重、轻和中间链组成的微管相关的运动蛋白复合物。在纤毛和鞭毛中发现的轴丝动力蛋白是附着在外周微管偶联物上的外侧和内侧动力蛋白臂的组成部分。DNaH2是轴突内臂Dynin重链（Chaselin et al.，1997 [PubMed 9256245 ]）[由OMIM，MAR 2008提供]。