FITC标记的DNAJA4蛋白抗体-抗体-抗体-生物在线
FITC标记的DNAJA4蛋白抗体

FITC标记的DNAJA4蛋白抗体

商家询价

产品名称: FITC标记的DNAJA4蛋白抗体

英文名称: Anti-DNAJA4/FITC

产品编号: HZ-14368R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
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  • 邮箱 : www.shzbio.net

 Rabbit Anti-DNAJA4/FITC Conjugated antibody

FITC标记的DNAJA4蛋白抗体

 

英文名称 Anti-DNAJA4/FITC
中文名称 FITC标记的DNAJA4蛋白抗体
别    名 DnaJ (Hsp40) homolog subfamily A member 4; DnaJ (Hsp40) homolog, subfamily A, member4; DNAJ A4; DnaJ homolog subfamily A member 4; DNAJA 4; DNAJA4; DNJA4_HUMAN; MST104; MSTP104; PRO1472.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJA4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Subcellular Location:
Membrane.

Similarity:
Contains 1 CR-type zinc finger.
Contains 1 J domain.

Database links:

Entrez Gene: 55466 Human

Entrez Gene: 528615 Cow

Entrez Gene: 58233 Mouse

Entrez Gene: 397613 Pig

Entrez Gene: 300721 Rat

SwissProt: Q8WW22 Human

SwissProt: Q9JMC3 Mouse

Unigene: 513053 Human

Unigene: 489676 Mouse

Unigene: 228618 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

DnaJ家族是所有伴侣家族中最大的家族之一,并且已经演化为具有多种细胞定位和功能的家族。J域的存在定义了作为DnaJ家族成员的蛋白质。DnaJ热休克诱导蛋白来源于大肠杆菌,受htpR调节蛋白的控制。DHNJ蛋白通过与HSP 70相互作用,在HSP 70伴侣机器中起关键作用,以刺激ATP水解。这些蛋白质含有富含半胱氨酸的区域,这些区域由锌指组成,锌指形成负责伴侣功能的肽结合结构域。DnaJ蛋白是蛋白水解的重要介质,参与蛋白质降解、胞吐和胞内吞的调节。DnaJA4(DnaJ同源亚家族A成员4)是SREBP调节的伴侣,被认为调节胆固醇生物合成途径。