FITC标记的DNAJB11蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的DNAJB11蛋白抗体
英文名称: Anti-DNAJB11/FITC
抗体货号: HZ-
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 9:43:00
详细资料:  实验方法技术资料
浏览人数:15
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-DNAJB11/FITC Conjugated antibody 

FITC标记的DNAJB11蛋白抗体

 

英文名称 Anti-DNAJB11/FITC
中文名称 FITC标记的DNAJB11蛋白抗体
别    名 ABBP-2; ABBP2; APOBEC1 binding protein 2; APOBEC1-binding protein 2; DJ9; DJB11_HUMAN; DnaJ (Hsp40) homolog subfamily B member 11; DnaJ homolog subfamily B member 11; DnaJ protein homolog 9; DNAJB11; EDJ; ER associated DNAJ; ER associated dnaJ protein 3; ER associated Hsp40 co chaperone; ER-associated DNAJ; ER-associated dnaJ protein 3; ER-associated Hsp40 co-chaperone; ERdj3; ERJ3; ERj3p; hDj-9; hDj9; HEDJ; Human DnaJ protein 9; PWP1 interacting protein 4; PWP1-interacting protein 4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJB11
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]

Function:
Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Subcellular Location:
Endoplasmic reticulum lumen. Associated with the ER membrane in a C-terminally epitope-tagged construct.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
Contains high-mannose Endo H-sensitive carbohydrates. Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known.

Similarity:
Contains 1 J domain.

Database links:

Entrez Gene: 51726 Human

Entrez Gene: 67838 Mouse

Entrez Gene: 360734 Rat

Omim: 611341 Human

SwissProt: Q9UBS4 Human

SwissProt: Q99KV1 Mouse

SwissProt: Q6TUG0 Rat

Unigene: 317192 Human

Unigene: 37516 Mouse

Unigene: 477367 Mouse

Unigene: 14603 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

DNAJB11属于进化上保守的DNAJ/HSP40蛋白家族,通过刺激ATP酶活性来调节分子伴侣活性。DNAJ蛋白可以具有多达3个不同的结构域:保守的70个氨基酸J结构域,通常在N端处;富含甘氨酸/丙氨酸(G/F)的区域;富含C端半胱氨酸的区域(Ohtsuka和Hata,2000[PubMed 11147971])。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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