FITC标记的DNAJC1蛋白抗体-抗体-抗体-生物在线
FITC标记的DNAJC1蛋白抗体

FITC标记的DNAJC1蛋白抗体

商家询价

产品名称: FITC标记的DNAJC1蛋白抗体

英文名称: Anti-DNAJC1/FITC

产品编号: HZ-14377R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-DNAJC1/FITC Conjugated antibody

FITC标记的DNAJC1蛋白抗体

 

英文名称 Anti-DNAJC1/FITC
中文名称 FITC标记的DNAJC1蛋白抗体
别    名 DnaJ (Hsp40) homolog subfamily C member 1; DnaJ homolog subfamily C member 1; DnaJ like protein; DnaJ protein homolog MTJ1; Dnajc1; DNAJL1; DNJC1_HUMAN; ERdj1; HTJ1; MGC131954; MTJ1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The DnaJ family comprises a group of chaperone proteins that contain a J domain and have diverse cellular localization and functions. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis and are also important mediators of proteolysis and protein degradation. DnaJC1 (DnaJ homolog subfamily C member 1), also designated MTJ1, HTJ1, ERdj1 or DNAJL1, is a 554 amino acid single-pass type I membrane protein found in the membrane of the endoplasmic reticulum, nucleus and microsome. DnaJC1 contains one J domain and two SANT domains, through which it interacts with GRP 78 and AACT, respectively. Via its cytosolic domain, DnaJC1 interacts with ribosomes and likely modulates protein synthesis. The gene encoding DnaJC1 maps to human chromosome 10p12.31 and mouse chromosome 2 A3.

Function:
May modulate protein synthesis.

Subcellular Location:
Endoplasmic reticulum membrane. Nucleus membrane. Microsome membrane.

Similarity:
Contains 1 J domain.
Contains 2 SANT domains.

Database links:

Entrez Gene: 64215 Human

Entrez Gene: 450344 Chimpanzee

Entrez Gene: 607587 Dog

Entrez Gene: 101125129 Gorilla

Entrez Gene: 13418 Mouse

Entrez Gene: 100455306 Orangutan

Entrez Gene: 100519794 Pig

Entrez Gene: 100341962 Rabbit

Entrez Gene: 291369 Rat

Entrez Gene: 704151 Rhesus monkey

Entrez Gene: 444260 Xenopus laevis

Entrez Gene: 496816 Xenopus tropicalis

Omim: 611207 Human

SwissProt: P82539 Dog

SwissProt: Q96KC8 Human

SwissProt: Q61712 Mouse

Unigene: 499000 Human

Unigene: 246674 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
   

DnaJ家族包括一组含有J结构域并具有多种细胞定位和功能的伴侣蛋白。DnaJ蛋白通过与HSP 70相互作用,刺激ATP水解,在HSP 70伴侣机制中起关键作用,也是蛋白水解和蛋白降解的重要介质。DnaJC1(DnaJ同源亚家族C成员1),也称为MTJ1、HTJ1、ERdj1或DNAJL1,是一种554个氨基酸的单程I型膜蛋白,存在于内质网、细胞核和微粒体的膜上。DNaJC1包含一个J域和两个桑特域,通过它们分别与GRP 78和AACT相互作用。通过其胞质结构域,DNaJC1与核糖体相互作用,并可能调节蛋白质合成。编码DAjJC1的基因定位于人类染色体10P1231和小鼠染色体2 A3。