FITC标记的DNAJC21蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的DNAJC21蛋白抗体
英文名称: Anti-DNAJC21/FITC
抗体货号: HZ-14387R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 10:09:00
详细资料:  实验方法技术资料
浏览人数:12
诚信指数:1030点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-DNAJC21/FITC Conjugated antibody 

FITC标记的DNAJC21蛋白抗体

 

英文名称 Anti-DNAJC21/FITC
中文名称 FITC标记的DNAJC21蛋白抗体
别    名 DJC21_HUMAN; DnaJ homolog subfamily A member 5; DnaJ homolog subfamily C member 21; DNAJA5; dnajc21; GS3; JJJ1; Protein GS3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJC21
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
With the presence of the J domain defining a protein as a member, the DnaJ family has evolved with diverse cellular localization and functions and is one of the largest chaperone families. DnaJ heat-shock-induced proteins are derived from the bacterium Escherichia coli and are controlled by the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions composed of zinc fingers that form a peptide-binding domain responsible for chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DNAJC21 (DnaJ homolog subfamily C member 21), also known as DNAJA5 or JJJ1, is a 531 amino acid protein that contains two C2H2-type zinc fingers and one J domain. Expressed in placenta, pancreas, kidney and brain, DNAJC21 may be a co-chaperone for HSP 70.

Function:
May act as a co-chaperone for HSP70.

Tissue Specificity:
Brain, placenta, kidney and pancreas.

Similarity:
Contains 2 C2H2-type zinc fingers.
Contains 1 J domain.

Database links:

Entrez Gene: 134218 Human

SwissProt: Q5F1R6 Human

Unigene: 131887 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

随着J结构域的存在,将蛋白质定义为成员,DnaJ家族已经进化为具有多种细胞定位和功能的家族,并且是最大的伴侣家族之一。DnaJ热休克诱导蛋白来源于大肠杆菌,由htpR调节蛋白控制。DNJ蛋白在HSP 70伴侣机器中与HSP 70相互作用以刺激ATP水解起关键作用。这个家族的成员含有富含半胱氨酸的区域,这些区域由锌指组成,锌指形成负责伴侣功能的肽结合结构域。DnaJ蛋白是蛋白水解的重要介质,参与蛋白质降解、胞吐和胞内吞的调节。DNAJC21(DnaJ同源亚家族C成员21)又称DNAJA5或JJJ1,是含有两个C2H2型锌指和一个J结构域的531个氨基酸蛋白。DNJC21在胎盘、胰腺、肾脏和脑中表达,可作为HSP 70的伴侣伴侣。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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