FITC标记的DNAJC21蛋白抗体
产品名称： FITC标记的DNAJC21蛋白抗体
英文名称： Anti-DNAJC21/FITC
产品编号： HZ-14387R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-DNAJC21/FITC Conjugated antibody
FITC标记的DNAJC21蛋白抗体
| 英文名称 | Anti-DNAJC21/FITC |
| 中文名称 | FITC标记的DNAJC21蛋白抗体 |
| 别 名 | DJC21_HUMAN; DnaJ homolog subfamily A member 5; DnaJ homolog subfamily C member 21; DNAJA5; dnajc21; GS3; JJJ1; Protein GS3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 62kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAJC21 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: With the presence of the J domain defining a protein as a member, the DnaJ family has evolved with diverse cellular localization and functions and is one of the largest chaperone families. DnaJ heat-shock-induced proteins are derived from the bacterium Escherichia coli and are controlled by the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions composed of zinc fingers that form a peptide-binding domain responsible for chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DNAJC21 (DnaJ homolog subfamily C member 21), also known as DNAJA5 or JJJ1, is a 531 amino acid protein that contains two C2H2-type zinc fingers and one J domain. Expressed in placenta, pancreas, kidney and brain, DNAJC21 may be a co-chaperone for HSP 70. Function: May act as a co-chaperone for HSP70. Tissue Specificity: Brain, placenta, kidney and pancreas. Similarity: Contains 2 C2H2-type zinc fingers. Contains 1 J domain. Database links: Entrez Gene: 134218 Human SwissProt: Q5F1R6 Human Unigene: 131887 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
随着J结构域的存在，将蛋白质定义为成员，DnaJ家族已经进化为具有多种细胞定位和功能的家族，并且是最大的伴侣家族之一。DnaJ热休克诱导蛋白来源于大肠杆菌，由htpR调节蛋白控制。DNJ蛋白在HSP 70伴侣机器中与HSP 70相互作用以刺激ATP水解起关键作用。这个家族的成员含有富含半胱氨酸的区域，这些区域由锌指组成，锌指形成负责伴侣功能的肽结合结构域。DnaJ蛋白是蛋白水解的重要介质，参与蛋白质降解、胞吐和胞内吞的调节。DNAJC21(DnaJ同源亚家族C成员21)又称DNAJA5或JJJ1，是含有两个C2H2型锌指和一个J结构域的531个氨基酸蛋白。DNJC21在胎盘、胰腺、肾脏和脑中表达，可作为HSP 70的伴侣伴侣。