Rabbit Anti-CD30/FITC Conjugated antibody
|别 名||CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8; TNR8_HUMAN; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen=CD30.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||肿瘤 细胞生物 细胞表面分子 细胞类型标志物|
|交叉反应||Mouse, Rat, Dog, Horse, Rabbit,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||64kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human CD30|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.
Cytoplasm and Cell membrane.
Phosphorylated on serine and tyrosine residues.
Contains 6 TNFR-Cys repeats.
Entrez Gene: 943 Human
Entrez Gene: 21941 Mouse
Omim: 153243 Human
SwissProt: P28908 Human
Unigene: 1314 Human
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
由该基因编码的蛋白质是TNF受体超家族的成员。这种受体是通过激活的，而不是通过休息、T和B细胞表达的。TRAF2和TRAF5可以与该受体相互作用，并介导信号转导，导致NF-kAb的活化。该受体是凋亡的阳性调节因子，并且已经表明限制了自身反应性CD8效应T细胞的增殖潜能并保护机体免受自身免疫的侵害。已经报道了编码不同亚型的该基因的两个交替剪接转录变体。[ RefSeq，JUL 2008 ]