Anti-CCL11抗体-抗体-抗体-生物在线
Anti-CCL11抗体

Anti-CCL11抗体

商家询价

产品名称: Anti-CCL11抗体

英文名称: CCL11

产品编号: YB--1601R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-CCL11抗体

产品编号 YB-1601R
英文名称 CCL11
中文名称 嗜酸粒细胞趋化因子/蛋白/Eotaxin抗体
别    名 Eotaxin 1; C-C motif chemokine 11; CCL 11; CCL11; CCL11_HUMAN; chemokine (C-C motif) ligand 11; Chemokine C C motif ligand 11; Chemokine CC Motif Ligand 11; Chemokine ligand 11; Eosinophil Chemotactic Protein; Eotaxin; eotaxin-1; MGC22554; SCYA 11; SCYA11; Small inducible cytokine A11; Small inducible cytokine subfamily A (Cys Cys) member 11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); Small inducible cytokine subfamily A member 11; Small-inducible cytokine A11;   
Specific References  (1)     |     bs-1601R has been referenced in 1 publications.
[IF=6.68] Cottle, Denny L., et al. "Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis." Human Molecular Genetics (2014): ddu459.  Mouse.  
PubMed:25209981
 
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 8kDa
细胞定位 细胞浆 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Eotaxin 1:24-97/97 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Jul 2008].

Function:
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.

Subcellular Location:
Secreted. 

Post-translational modifications:
O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

SWISS:
P51671

Gene ID:
6356

Database links:

Entrez Gene: 6356 Human

Omim: 601156 Human

SwissProt: P51671 Human

Unigene: 54460 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

Eotaxin-1嗜酸粒细胞趋化蛋白参与过敏性炎症的嗜酸粒细胞的分化、成熟、内皮粘附和滚动、趋化,参与浸润、活化和释放毒性蛋白,参与炎性介质的过程.
产品图片
Images kindly provided by Dr. Denny Cottle from the publication, Fetal inhibition of inflammation improves disease phenotypes in Harlequin Ichthyosis.Formalin-fixed and paraffin embedded mouse skin probed with Rabbit Anti- CCL11/Eotaxin 1 Polyclonal Antibody (bs-1601R) at 1:100 for two hours at room temperature (green channel).