FITC标记的选择性剪接因子3亚基3抗体
产品名称： FITC标记的选择性剪接因子3亚基3抗体
英文名称： Anti-SF3A3/FITC
产品编号： HZ-19677R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-SF3A3/FITC Conjugated antibody
FITC标记的选择性剪接因子3亚基3抗体
| 英文名称 | Anti-SF3A3/FITC |
| 中文名称 | FITC标记的选择性剪接因子3亚基3抗体 |
| 别 名 | Pre mRNA splicing factor SF3a (60kD); Pre mRNA splicing factor SF3a; PRP 9; PRP9; PRPF 9; PRPF9; SAP 61; SAP61; SF3A3; SF3a60; Spliceosome associated protein 61; Splicing factor 3a subunit 3 60kDa; Splicing factor 3a subunit 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 59kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SF3A3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. [provided by RefSeq, Jul 2008] Function: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Subunit: Identified in the spliceosome C complex. Component of splicing factor SF3A which is composed of three subunits; SF3A3/SAP61, SF3A2/SAP62, SF3A1/SAP114. SF3A associates with the splicing factor SF3B and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex (U2 snRNP). Interacts with SF3A1, through its N-terminal region. Subcellular Location: Nucleus speckle. Tissue Specificity: Ubiquitous. Similarity: Belongs to the SF3A3 family. Database links: Entrez Gene: 419608 Chicken Entrez Gene: 523250 Cow Entrez Gene: 475326 Dog Entrez Gene: 10946 Human Entrez Gene: 75062 Mouse Entrez Gene: 100512288 Pig Entrez Gene: 313583 Rat Entrez Gene: 495359 Xenopus laevis Entrez Gene: 446168 Zebrafish Omim: 605596 Human SwissProt: Q12874 Human SwissProt: Q9D554 Mouse Unigene: 77897 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码剪接因子3A蛋白复合物的亚基3。剪接因子3a异三聚体包括亚基1、2和3，并且对于将15S U2 snRNP体外转化成执行前mRNA剪接的活性17S颗粒是必要的。亚基3通过其氨基末端与亚基1相互作用，而亚基3的锌指结构域在其与15S U2 snRNP的结合中起作用。这个基因在第20号染色体上有假基因。[ RefSeq，JUL 2008 ]