Anti-EXOC8抗体
产品名称： Anti-EXOC8抗体
英文名称： EXOC8
产品编号： YB--14665R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-EXOC8抗体
| 产品编号 | YB-14665R |
| 英文名称 | EXOC8 |
| 中文名称 | EXOC8蛋白抗体 |
| 别 名 | EXO84; Exo84p; exoc8; EXOC8_HUMAN; Exocyst complex 84 kDa subunit; Exocyst complex component 8; SEC84. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 82kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EXOC8:311-410/725 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. Exo84 (Exocyst complex 84 kDa subunit), also known as Exocyst complex component 8, is a 725 amino acid protein that is one of eight protein subunits composing the mammalian exocyst complex. Both Exo84 and Sec5 are effector targets for active Ral GTPases, which are responsible for regulating exocyst complex activities. Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subcellular Location: Cytoplasm. Cell projection > growth cone. Redistributes to growing neurites and growth cones during cell differentiation (By similarity). Binds lipids with phosphatidylinositol-3,4,5-trisphosphate groups. Similarity: Belongs to the EXO84 family. Contains 1 PH domain. SWISS: Q8IYI6 Gene ID: 149371 Database links: Entrez Gene: 149371 Human Entrez Gene: 102058 Mouse Omim: 615283 Human SwissProt: Q8IYI6 Human SwissProt: Q6PGF7 Mouse Unigene: 356198 Human Unigene: 347360 Mouse Unigene: 392449 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |
 Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EXOC8) Polyclonal Antibody, Unconjugated (bs-14665R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining
|