FITC标记的皮肤T细胞虏获趋化因子抗体
产品名称： FITC标记的皮肤T细胞虏获趋化因子抗体
英文名称： Anti-CCL27/FITC
产品编号： HZ-20841R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-CCL27/FITC Conjugated antibody
FITC标记的皮肤T细胞虏获趋化因子抗体
| 英文名称 | Anti-CCL27/FITC |
| 中文名称 | FITC标记的皮肤T细胞虏获趋化因子抗体 |
| 别 名 | ALP; CTACK; C-C motif chemokine 27; CC chemokine ILC; Ccl27; CTAK; Cutaneous T cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL 11 R alpha locus chemokine; IL-11 R-alpha-locus chemokine; PESKY; SCYA27; Skinkine; Small inducible cytokine A27; Small-inducible cytokine A27. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 趋化因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCL27 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq]. Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10. Subunit: Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization. Subcellular Location: Secreted. Tissue Specificity: Testis, thymus, placenta, ovary and skin. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 100039863 Mouse Entrez Gene: 100039939 Mouse Entrez Gene: 100040048 Mouse Entrez Gene: 20301 Mouse Entrez Gene: 362505 Rat SwissProt: Q9Z1X0 Mouse Unigene: 335946 Mouse Unigene: 425176 Mouse Unigene: 484274 Mouse Unigene: 6660 Mouse Unigene: 78371 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CCL27是一种CC型趋化因子，又被称为Skinkine，ESkine和CTACK。CCL27基因位于人类染色体9，它与皮肤上归巢的记忆T淋巴细胞有关，并在T细胞介导的皮肤炎症中起着重要的作用。CCL27表达在许多组织，包括性腺，胸腺，胎盘和皮肤。其配体为CCR10,CCL27与接触性软疣病毒编码产生的蛋白质MC148有较高的同源性，但却与人疱疹病毒8型编码产生病毒巨噬细胞炎症蛋白-Ⅱ竞争结合受体CCR10 |
该基因是在9号染色体的P臂上聚集的几种CC细胞因子基因之一。细胞因子是一类参与免疫调节和炎症过程的分泌蛋白。CC细胞因子是由两个相邻半胱氨酸表征的蛋白质。该基因编码的蛋白是趋化性皮肤相关记忆T淋巴细胞。这种细胞因子也可以发挥作用，介导淋巴细胞归巢到皮肤部位。它特异性结合趋化因子受体10（CCR10）。对类似小鼠蛋白的研究表明，这些蛋白-受体相互作用在T细胞介导的皮肤炎症中起着关键作用。