Rabbit Anti-TIMM8B/FITC Conjugated antibody
|别 名||DDP2; Deafness dystonia protein 2; FLJ21744; MGC102866; MGC117373; Mitochondrial import inner membrane translocase subunit Tim8 B; Small zinc finger like protein DDP2; TIM8B; ranslocase of inner mitochondrial membrane 8 homolog B (yeast); Translocase of inner mitochondrial membrane 8 homolog b;|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||肿瘤 细胞生物 线粒体|
|交叉反应||Human, Mouse, Rat,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||9kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human TIMM8B|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009]
Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Heterohexamer; possibly composed of 3 copies of TIMM8B and 3 copies of TIMM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIMM22 (By similarity).
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Belongs to the small Tim family.
Entrez Gene: 26521 Human
Entrez Gene: 30057 Mouse
Entrez Gene: 64372 Rat
Omim: 606659 Human
SwissProt: Q9Y5J9 Human
SwissProt: P62077 Mouse
SwissProt: P62078 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications