FITC标记的硫酸软骨素聚合酶3抗体
产品名称： FITC标记的硫酸软骨素聚合酶3抗体
英文名称： Anti-CSGLCAT/FITC
产品编号： HZ-20304R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CSGLCAT/FITC Conjugated antibody
FITC标记的硫酸软骨素聚合酶3抗体
| 英文名称 | Anti-CSGLCAT/FITC |
| 中文名称 | FITC标记的硫酸软骨素聚合酶3抗体 |
| 别 名 | Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; CSGlcA-T; ChSy 3; ChSy-3; CHPF2; ChPF-2; CSGLCA T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; CHPF2_HUMAN; Chondroitin polymerizing factor 2; Chondroitin sulfate glucuronyltransferase; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 糖蛋白 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 86kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CSGLCAT |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely expressed and existing as two alternatively spliced isoforms, CSGlcA-T is found at highest levels in small intestine, pancreas and placenta, with lower levels in heart, brain, kidney, and skeletal muscle where it transfers glucuronic acid from UDP-glucuronic acid to N-acetylgalactosamine residues of elongating chondroitin polymers. The gene encoding CSGlcA-T maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome and Lissencephaly. Function: Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable). Tissue Specificity: Ubiquitous. Highly expressed in placenta, small intestine and pancreas. Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family Database links: Entrez Gene: 54480 Human Entrez Gene: 100910 Mouse Entrez Gene: 296733 Rat Omim: 608037 Human SwissProt: Q9P2E5 Human Unigene: 647084 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CSGlcA-T是属于软骨素N-乙酰半乳糖胺基转移酶家族的高尔基体的772氨基酸单程II型膜蛋白。CSGlcA-T广泛表达并作为两种可选择的剪接异构体存在，在小肠、胰腺和胎盘中含量最高，在心脏、大脑、肾脏和骨骼肌中含量较低，在骨骼肌中它把葡萄糖醛酸从UDP-葡萄糖醛酸转移到N-乙酰半乳糖胺。伸长软骨素聚合物的特征。编码CSGlcA-T的基因定位于人类7号染色体，其中包含1000多个基因，占人类基因组的近5%。第7号染色体与成骨不全、PAND综合征和Lissencephaly有关。