FITC标记的神经细胞粘附蛋白NGN抗体
产品名称： FITC标记的神经细胞粘附蛋白NGN抗体
英文名称： Anti-Neogenin/FITC
产品编号： HZ-20422R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
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- 邮箱 : www.shzbio.net
Rabbit Anti-Neogenin/FITC Conjugated antibody
FITC标记的神经细胞粘附蛋白NGN抗体
| 英文名称 | Anti-Neogenin/FITC |
| 中文名称 | FITC标记的神经细胞粘附蛋白NGN抗体 |
| 别 名 | NGN; Neo1; Neo 1; Neogenin; NEO1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 细胞粘附分子 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 156kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Neogenin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq, Feb 2010]. Function: Neogenin is one of several netrin-binding proteins. Neogenin functions as an Repulsive Guidance Molecule (RGM) receptor; RGM is implicated in axonal guidance and neural tube closure. Subunit: Interacts with RGMA. Interacts with MYO10 Subcellular Location: Cell membrane; Single-pass type I membraneprotein. Tissue Specificity: Widely expressed and also in cancer celllines. Similarity: Belongs to the immunoglobulin superfamily. DCC family. Contains 6 fibronectin type-III domains. Contains 4 Ig-like C2-type (immunoglobulin-like)domains. Database links: Entrez Gene: 4756 Human Entrez Gene: 18007 Mouse Entrez Gene: 81735 Rat Omim: 601907 Human SwissProt: Q92859 Human SwissProt: P97798 Mouse SwissProt: P97603 Rat Unigene: 388613 Human Unigene: 42249 Mouse Unigene: 10667 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码作为免疫球蛋白超家族成员的细胞表面蛋白。编码蛋白由4个N端免疫球蛋白样结构域、6个纤维连接蛋白III结构域、一个跨膜结构域和一个C端内结构域组成，它们与肿瘤抑制候选基因DCC具有同源性。这种蛋白质可能参与细胞生长和分化和细胞-细胞粘附。在某些癌症中，该基因的缺陷与细胞增殖有关。交替转录结果在多个转录变体。[由ReFSEQ提供，FEB 2010 ]。