FITC标记的嗜酸粒细胞趋化蛋白CCL6抗体
产品名称: FITC标记的嗜酸粒细胞趋化蛋白CCL6抗体
英文名称: Anti-CCL6/FITC
产品编号: HZ-20464R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CCL6/FITC Conjugated antibody
FITC标记的嗜酸粒细胞趋化蛋白CCL6抗体
英文名称 | Anti-CCL6/FITC |
中文名称 | FITC标记的嗜酸粒细胞趋化蛋白CCL6抗体 |
别 名 | C-C motif chemokine 6; C10; CCL 6; Chemokine C C motif Ligand 6; Chemokine C-C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 10kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCL6 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: CCL6 (C10) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. It is a potent chemoattractant of macrophages, but it can also attract B cells, CD4+ lymphocytes and eosinophils. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be induced under conditions suitable for myeloid cell differentiation. CCL6 (C10) was originally identified as a transcript that is induced in bone marrow cells upon stimulation of GMCSF. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1. Function: CCL6(22-95) and CCL6(23-95) are potent chemoattractants. Subcellular Location: Secreted. Tissue Specificity: Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 20305 Mouse Entrez Gene: 287910 Rat SwissProt: P27784 Mouse SwissProt: Q68FP3 Rat Unigene: 137 Mouse Unigene: 7857 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CCL6(C10)是一种小细胞因子,属于CC趋化因子家族,仅见于啮齿动物。它是一种强有力的巨噬细胞趋化剂,但也能吸引B细胞、CD4+淋巴细胞和嗜酸性粒细胞。在小鼠中,CCL6在中性粒细胞和巨噬细胞系的细胞中表达,并且可以在适合骨髓细胞分化的条件下诱导。CCL6(C10)最初被鉴定为在GMCSF的刺激下在骨髓细胞中诱导的转录本。CCR6的细胞表面受体被认为是趋化因子受体CCR1。