FITC标记的巨噬细胞炎性蛋白15上海沪震实业有限公司

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产品名称: FITC标记的巨噬细胞炎性蛋白15
英文名称: Anti-CCL15/FITC
抗体货号: HZ-20465R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/12/5 15:25:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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邮编:
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电话:
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传真:
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上海·中国-上海
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产品详细描述

 Rabbit Anti-CCL15/FITC Conjugated antibody 

FITC标记的巨噬细胞炎性蛋白15

 

英文名称 Anti-CCL15/FITC
中文名称 FITC标记的巨噬细胞炎性蛋白15
别    名 C-C motif chemokine 15; Small inducible cytokine A15; CC chemokine 3; CCL15; Chemokine CC2; HCC2; HMRP2B; CCL15_HUMAN; Leukotactin 1; Macrophage inflammatory protein 5; LKN1; MIP1 delta; MIP1d; MIP5; MIP 5; MIP-5; Mrp2b; NCC3; SCYA15; SCYL3; SY15.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCL15
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene, chemokine (C-C motif) ligand 15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene, chemokine (C-C motif) ligand 14, and are represented as GeneID: 348249. [provided by RefSeq].

Function:
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. 

Subunit:
Monomer. 

Subcellular Location:
Secreted. 

Tissue Specificity:
Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.

Similarity:
Belongs to the intercrine beta (chemokine CC) family. 

Database links:

Entrez Gene: 6359 Human

Omim: 601393 Human

SwissProt: Q16663 Human

Unigene: 272493 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application

该基因是趋化因子(C-C基序)配体15,是聚集在17q11.2上的几个CC细胞因子基因之一。CC细胞因子是由两个相邻半胱氨酸表征的分泌蛋白。该基因编码的细胞因子对T细胞和单核细胞具有趋化性,诱导单核细胞释放N-乙酰-β-D-氨基葡萄糖苷酶。它诱导单核细胞内钙浓度的变化,被认为通过CCR1受体起作用。表达包括来自下游细胞因子基因、趋化因子(C-C基序)配体14的外显子的读出转录本,并表示为GeneID:348249。[由RefSeq提供]。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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