FITC标记的小核糖核蛋白N抗体上海沪震实业有限公司

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产品名称: FITC标记的小核糖核蛋白N抗体
英文名称: Anti-SNRPN/FITC
抗体货号: HZ-8741R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/12/6 11:18:00
详细资料:  实验方法技术资料
浏览人数:5
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-SNRPN/FITC Conjugated antibody

FITC标记的小核糖核蛋白N抗体

 

英文名称 Anti-SNRPN/FITC
中文名称 FITC标记的小核糖核蛋白N抗体
别    名 HCERN3; PWCR; RSMN_HUMAN; RT LI; RTLI; SM D; Sm N; Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein associated protein N; Small nuclear ribonucleoprotein polypeptide N; Small nuclear ribonucleoprotein-associated protein N; SMD; SmN; SNRNP N; snRNP-N; SNRNPN; SNRPN; SNURF SNRPN; Tissue specific splicing protein; Tissue-specific-splicing protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNRPN
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]

Function:
May be involved in tissue-specific alternative RNA processing events.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in brain and lymphoblasts.

Similarity:
Belongs to the snRNP SmB/SmN family.

Database links:

Entrez Gene: 780877 Cow

Entrez Gene: 6638 Human

Entrez Gene: 20646 Mouse

Entrez Gene: 84704 Mouse

Entrez Gene: 81781 Rat

Omim: 182279 Human

SwissProt: Q17QN3 Cow

SwissProt: Q60HD3 Cynomolgus Monkey

SwissProt: P63162 Human

SwissProt: P63163 Mouse

SwissProt: Q5R6I0 Orangutan

SwissProt: P63164 Rat

Unigene: 555970 Human

Unigene: 564847 Human

Unigene: 578619 Human

Unigene: 585703 Human

Unigene: 592473 Human

Unigene: 621316 Human

Unigene: 632166 Human

Unigene: 728856 Human

Unigene: 274995 Mouse

Unigene: 11169 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因位于15号染色体上的Prader-Willi综合征关键区域,由父本等位基因印迹和表达。它编码小核糖核蛋白复合物的一个组成部分,在mRNA前处理中起作用,并可能有助于组织特异性的替代性剪接。选择性启动子的使用和选择性剪接导致许多编码相同蛋白的转录体变体。起始于CpG岛相关印迹中心的转录变体可以是双电子的,并且还编码来自上游开放阅读框架的SNRPN上游阅读框架蛋白(SNURF)。此外,小核仁RNA宿主基因14(SNHG14)的长剪接转录本可能起源于该位点的启动子,并与该基因共享外显子。这一区域的变化与父母的印记切换失败有关,这可能导致Angelman综合征或Prader-Willi综合征。〔RefSeq,2017〕

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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