|别 名||Fibin; FIBIN_HUMAN; Fin bud initiation factor homolog (zebrafish); Fin bud initiation factor homolog; MGC24932; PSEC0235.|
|规格价格||100ul/1380元 购买 200ul/2200元 购买 大包装/询价|
|说 明 书||100ul 200ul|
|交叉反应||Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,|
|产品应用||WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||22kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human FIBIN:101-200/211|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
FIBIN (Fin bud initiation factor homolog) is a 211 amino acid protein involved in fin initiation in zebrafish. The human homolog is encoded by a gene that maps to chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Secreted. Golgi apparatus.
Belongs to the FIBIN family.
Entrez Gene: 387758 Human
Entrez Gene: 451086 Chimpanzee
Entrez Gene: 507975 Cow
Entrez Gene: 100057578 Horse
Entrez Gene: 67606 Mouse
Entrez Gene: 499856 Rat
Entrez Gene: 699699 Rhesus monkey
SwissProt: Q5E9H1 Cow
SwissProt: A4UZ23 Horse
SwissProt: Q8TAL6 Human
SwissProt: Q9CQS3 Mouse
SwissProt: Q5U2T4 Rat
Unigene: 712718 Human
Unigene: 291809 Mouse
Unigene: 43451 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.