Anti-ZNF649抗体上海钰博生物科技有限公司

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产品名称: Anti-ZNF649抗体
英文名称: ZNF649
抗体货号: YB--16103R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1380元
抗原: KLH conjugated synthetic peptide derived from human ZNF649:401-505/505
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2018/12/6 13:25:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-ZNF649抗体

产品编号 YB-16103R
英文名称 ZNF649
中文名称 锌指蛋白649抗体
别    名 FLJ12644; Zinc finger protein 649; ZN649_HUMAN; ZNF649.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF649:401-505/505 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 649 (ZNF649) is a 505 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF649 is highly expressed in heart, brain and skeletal muscle with lower levels of expression in lung, liver, kidney and pancreas. ZNF649 contains ten C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional repression of mitogen-activated protein kinase signaling pathways.

Function:
Transcriptional repressor. Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in heart, skeletal muscle, and brain. Lower expression in liver, lung, kidney, pancreas and placenta.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 10 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
Q9BS31

Gene ID:
65251

Database links:

Entrez Gene: 65251 Human

Omim: 611903 Human

SwissProt: Q9BS31 Human

Unigene: 148322 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Sample: 
HL60(Human) Cell Lysate at 30 ug
Primary: Anti-ZNF649 (bs-16103R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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