Anti-ZNHIT2抗体上海钰博生物科技有限公司

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产品名称: Anti-ZNHIT2抗体
英文名称: ZNHIT2
抗体货号: YB--16415R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1380元
抗原: KLH conjugated synthetic peptide derived from human ZNHIT2:51-150/403
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Pig,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2018/12/6 14:44:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-ZNHIT2抗体

产品编号 YB-16415R
英文名称 ZNHIT2
中文名称 ZNHIT2蛋白抗体
别    名 C11orf5; FON; MGC120285; MGC120286; OTTHUMP00000230419; Protein FON; Zinc finger HIT domain-containing protein 2; Zinc finger HIT type containing 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; ZNHI2_HUMAN; ZNHIT2.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, 
产品应用 WB=1:500-2000 ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNHIT2:51-150/403 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
ZNHIT2 (zinc finger, HIT-type containing 2), also known as FON, is a 403 amino acid protein that is highly expressed in the seminiferous tubules of testis, with low expression in other tissues. Containing one HIT-type zinc finger, ZNHIT2 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Tissue Specificity:
Low expression in most tissues; highly expressed in testis.

Similarity:
Contains 1 HIT-type zinc finger.

SWISS:
Q9UHR6

Gene ID:
741

Database links:

Entrez Gene: 741 Human

Entrez Gene: 539138 Cow

Entrez Gene: 100514699 Pig

Entrez Gene: 309177 Rat

Omim: 604575 Human

SwissProt: Q2TBW5 Cow

SwissProt: Q9UHR6 Human

Unigene: 41757 Cow

Unigene: 121025 Human

Unigene: 19362 Pig

Unigene: 18470 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Protein: bladder(mouse) lysates at 40ug;
Primary: Rabbit Anti-ZNHIT2 (bs-16415R) at 1:300; 
Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; 
Predicted band size:45 kD Observed band size:45 kD

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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