Anti-DYDC1抗体-抗体-抗体-生物在线
Anti-DYDC1抗体

Anti-DYDC1抗体

商家询价

产品名称: Anti-DYDC1抗体

英文名称: DYDC1

产品编号: YB--8286R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-DYDC1抗体

产品编号 YB-8286R
英文名称 DYDC1
中文名称 DYDC1蛋白抗体
别    名 DPY30 domain-containing protein 1; DPY30D1; DYDC1; DYDC1_HUMAN; RSD 9; RSD9.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  发育生物学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DYDC1:101-177/177 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
PubMed PubMed
产品介绍 background:
The Dumpy-30 (DPY-30) protein was first described in C. elegans, in which it is involved in dosage compensation of sex chromosomes. Conserved from yeast to humans, the DPY-30 family is involved in gene expression and chromatin modification, specifically histone methylation. DPY-30 and closely related proteins contain a short motif that is related to the dimerization motif in the regulatory subunit of protein kinase A (PKA), which consists of two ?helices that form a four-helix bundle during dimerization. As a member of the DPY-30 family, DYDC1 (DPY30 domain-containing protein 1), also known as DPY30D1 and RSD9, is a 177 amino acid protein that binds to Endophilin III and plays a crucial role during acrosome biogenesis. DYDC1 is specifically expressed in brain and testis and accumulates in the acrosome area during spermatogenesis. Knockdown of DYDC1 mRNA results in disruption of acrosome formation and spermatid differentiation.

Function:
Plays a crucial role during acrosome biogenesis. 

Subunit:
Interacts with SH3GL3. 

Tissue Specificity:
Brain and testis. Accumulates during late stage of spermiogenesis.

Similarity:
Belongs to the dpy-30 family. 

SWISS:
Q8WWB3

Gene ID:
143241

Database links:

Entrez Gene: 143241 Human

Entrez Gene: 69496 Mouse

Entrez Gene: 688433 Rat

SwissProt: Q32LH1 Cow

SwissProt: Q8WWB3 Human

SwissProt: Q9D9T0 Mouse

Unigene: 407751 Human

Unigene: 55734 Mouse

Unigene: 157879 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application