Anti-TMEM147抗体上海钰博生物科技有限公司

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产品名称: Anti-TMEM147抗体
英文名称: TMEM147
抗体货号: YB--8336R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1580元
抗原: KLH conjugated synthetic peptide derived from human TMEM147:51-150/224
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/1/11 11:09:00
详细资料:  实验方法技术资料
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诚信指数:1562点
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-TMEM147抗体

产品编号 YB-8336R
英文名称 TMEM147
中文名称 跨膜蛋白147抗体
别    名 ransmembrane protein 147; Full=Protein NIFIE 14; TM147_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  神经生物学  信号转导  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMEM147:51-150/224 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
PubMed PubMed
产品介绍 background:
TMEM147, also known as ; NIFIE 14, is a 224 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Subunit:
Forms a complex with NCLN and NOMO2, resulting in a stabilization of the 3 proteins, which are otherwise quickly degraded by the proteasome. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, probably also interacts with NOMO1 and NOMO3. 

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein. 

SWISS:
Q9BVK8

Gene ID:
10430

Database links:

Entrez Gene: 10430 Human

Entrez Gene: 69804 Mouse

Entrez Gene: 292792 Rat

SwissProt: Q9BVK8 Human

SwissProt: Q9CQG6 Mouse

SwissProt: Q2TA63 Rat

Unigene: 9234 Human

Unigene: 27499 Mouse

Unigene: 66215 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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