Anti-HAND2抗体上海钰博生物科技有限公司

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产品名称: Anti-HAND2抗体
英文名称: HAND2
抗体货号: YB--6935R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1580元
抗原: KLH conjugated synthetic peptide derived from human HAND2:101-200/217
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/3/19 11:03:00
详细资料:  实验方法技术资料
浏览人数:36
诚信指数:1658点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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上海钰博生物科技有限公司
地址:
上海市沪闵路6088号龙之梦大厦8楼806室
邮编:
200612
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顾磊
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上海·上海
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产品详细描述

 Anti-HAND2抗体

产品编号 YB-6935R
英文名称 HAND2
中文名称 心脏和神经嵴衍生蛋白2抗体
别    名 DHAND 2; dHAND; DHAND2; Ehand 2; Ehand2; FLJ16260; HAND 2; Hand2; autonomic nervous system and neural crest derivatives-expressed protein 2; heart; Basic helix loop helix transcription factor HAND2; bHLHa26; Class A basic helix-loop-helix protein 26; Deciduum; Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody HAND2_HUMAN; Heart and neural crest derivatives expressed 2; Heart and neural crest derivatives expressed protein 2; heart and neural crest derivatives expressed transcript 2; Heart- and neural crest derivatives-expressed protein 2; Hed; Highly similar to dHAND M musculus; MGC125303; MGC125304; Th 2; Th2; Thing 2; Thing2.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 心血管  细胞生物  免疫学  发育生物学  神经生物学  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HAND2:101-200/217 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.

Function:
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Forms homodimers and heterodimers with TCF3 gene products E12 and E47, HAND1 and HEY1, HEY2 and HEYL (hairy-related transcription factors).

Subcellular Location:
Nucleus.

Tissue Specificity:
Heart.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.

SWISS:
P61296

Gene ID:
9464

Database links:

Entrez Gene: 9464 Human

Entrez Gene: 15111 Mouse

Entrez Gene: 64637 Rat

Entrez Gene: 58150 Zebrafish

Omim: 602407 Human

SwissProt: Q90690 Chicken

SwissProt: P61296 Human

SwissProt: Q61039 Mouse

SwissProt: P61295 Rat

SwissProt: P57102 Zebrafish

Unigene: 388245 Human

Unigene: 261588 Mouse

Unigene: 430844 Mouse

Unigene: 36496 Rat

Unigene: 41057 Rat

Unigene: 81423 Zebrafish

Unigene: 8328 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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