|别 名||DCA11_HUMAN; DCAF11; DDB1 and CUL4 associated factor 11; DDB1- and CUL4-associated factor 11; DKFZp779A1629; GL014; OTTHUMP00000164696; PRO2389; WD repeat domain 23; WD repeat-containing protein 23; WDR23.|
|规格价格||100ul/1580元 购买 200ul/2480元 购买 大包装/询价|
|说 明 书||100ul 200ul|
|交叉反应||Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,|
|产品应用||WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||62kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human WDR23:141-220/220|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR23 (WD-repeat-containing protein 23), also known as GL014 or PRO2389, is a 546 amino acid protein that contains seven WD-repeats. WDR23 is expressed as three isoforms due to alternative splicing events.
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Interacts with DDB1 and CUL4A.
Contains 7 WD repeats.
Entrez Gene: 80344 Human
Entrez Gene: 28199 Mouse
Entrez Gene: 305895 Rat
Omim: 613317 Human
SwissProt: Q8TEB1 Human
SwissProt: Q91VU6 Mouse
SwissProt: Q5M9G8 Rat
Unigene: 525251 Human
Unigene: 11535 Mouse
Unigene: 16542 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications