Anti-FbxW2抗体-抗体-抗体-生物在线
Anti-FbxW2抗体

Anti-FbxW2抗体

商家询价

产品名称: Anti-FbxW2抗体

英文名称: FbxW2

产品编号: YB--8393R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-FbxW2抗体

产品编号 YB-8393R
英文名称 FbxW2
中文名称 FbxW2蛋白抗体
别    名 F box and WD 40 domain containing protein 2; F box and WD repeat domain containing 2; F Box and WD40 Domain Protein 2; F box/WD repeat containing protein 2; FBW 2; FBW2; FBXW 2; Fwd2; Md6; Protein MD6.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FbxW2:321-420/454 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.

Subunit:
Directly interacts with SKP1 and CUL1.

Subcellular Location:
Nuclear

Similarity:
Contains 1 F-box domain.
Contains 4 WD repeats.

SWISS:
Q9UKT8

Gene ID:
26190 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.