|别 名||Brix domain-containing protein 1: brix domain containing 1; Brix domain containing protein 1; homolog of Rpf2 (S. cerevesiae); ribosomal processing factor 2 homolog; RPF2; RPF2_HUMAN.|
|规格价格||100ul/1580元 购买 200ul/2480元 购买 大包装/询价|
|说 明 书||100ul 200ul|
|交叉反应||Human, Mouse, Rat, Chicken, Dog, Cow, Horse,|
|产品应用||WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||36kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human BXDC1:231-306/306|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
BXDC1 is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.
BXDC proteins interact with the 5S, 5.8S and 28S RNAs of large ribosomal subunits.
Nucleus, nucleolus. Note=Associated with the nucleolus in an RNA-dependent manner.
Belongs to the RPF2 family.
Contains 1 Brix domain.
Entrez Gene: 84154 Human
Entrez Gene: 67239 Mouse
Entrez Gene: 294436 Rat
SwissProt: Q2YDN6 Cow
SwissProt: Q9H7B2 Human
SwissProt: Q9JJ80 Mouse
Unigene: 372265 Human
Unigene: 11480 Mouse
Unigene: 25279 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications