|别 名||COX7A2; Cytochrome c oxidase polypeptide VIIa-liver/heart; mitochondrial precursor (Cytochrome c oxidase subunit VIIa-L) (VIIaL); CX7A2_HUMAN.|
|规格价格||100ul/1580元 购买 200ul/2480元 购买 大包装/询价|
|说 明 书||100ul 200ul|
|研究领域||肿瘤 细胞生物 免疫学 信号转导 线粒体|
|交叉反应||Human, Mouse, Rat, Cow, Sheep,|
|产品应用||ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||6.7kDa|
|细胞定位||细胞浆 细胞膜 线粒体|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human COX7A2:21-80/83|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1(muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009].
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Mitochondrion inner membrane
Belongs to the cytochrome c oxidase VIIa family.
Entrez Gene: 1347 Human
o Entrez Gene: 12866 Mouse
o Entrez Gene: 29507 Rat
o Omim: 123996 Human
o SwissProt: P14406 Human
o SwissProt: P48771 Mouse
o SwissProt: P35171 Rat
o Unigene: 70312 Human
o Unigene: 152627 Mouse
o Unigene: 1745 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.