Anti-HIG1/HIGD1A抗体上海钰博生物科技有限公司

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产品名称: Anti-HIG1/HIGD1A抗体
英文名称: HIG1/HIGD1A
抗体货号: YB--9066R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1580元
抗原: KLH conjugated synthetic peptide derived from human HIG1/HIGD1A:25-70/93
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Horse,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/3/21 12:06:00
详细资料:  实验方法技术资料
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诚信指数:1562点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-HIG1/HIGD1A抗体

产品编号 YB-9066R
英文名称 HIG1/HIGD1A
中文名称 缺氧诱导基因1蛋白/HIGD1A抗体
别    名 Hig1; HIG1 domain family member 1A; HIG1 domain family, member 1A; HIG1 hypoxia inducible domain family, member 1A; HIG1A_HUMAN; HIGD1A; HIMP1; Hypoxia-inducible gene 1 protein.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HIG1/HIGD1A:25-70/93 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
HIGD1A (HIG1 domain family member 1A), also known as HIG1 (hypoxia-inducible gene 1 protein) or HSPC010, is a 93 amino acid multi-pass membrane protein that contains one HIG1 domain. Existing as two alternatively spliced isoforms, the gene encoding HIGD1A maps to human chromosome 3, which contains approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes. 

Subunit:
Associates with cytochrome c oxidase (COX, complex IV); proposed complex component. Also associates with respratory chain supercomplexes.

Subcellular Location:
Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane (Probable).

Similarity:
Contains 1 HIG1 domain.

SWISS:
Q9Y241

Gene ID:
25994

Database links:

Entrez Gene: 25994 Human

Entrez Gene: 56295 Mouse

Entrez Gene: 140937 Rat

SwissProt: Q9Y241 Human

SwissProt: Q9JLR9 Mouse

SwissProt: Q8VH49 Rat

Unigene: 593134 Human

Unigene: 728813 Human

Unigene: 7917 Human

Unigene: 347915 Mouse

Unigene: 2084 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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