Anti-BAGE2 + BAGE3抗体-抗体-抗体-生物在线
Anti-BAGE2 + BAGE3抗体

Anti-BAGE2 + BAGE3抗体

商家询价

产品名称: Anti-BAGE2 + BAGE3抗体

英文名称: BAGE2 + BAGE3

产品编号: YB--9114R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 所在区域 : 上海
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 Anti-BAGE2 + BAGE3抗体

产品编号 YB-9114R
英文名称 BAGE2 + BAGE3
中文名称 肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体
别    名 B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN; B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BAGE2 and BAGE2:55-109/109 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.

Function:
Unknown. Candidate gene encoding tumor antigens.

Subcellular Location:
Secreted.

Tissue Specificity:
Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.

Similarity:
Belongs to the BAGE family.

SWISS:
Q86Y30

Gene ID:
85319

Database links:

Entrez Gene: 85319 Human

SwissProt: Q86Y30 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications