Anti-MFGE8/BA46抗体上海钰博生物科技有限公司

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产品名称: Anti-MFGE8/BA46抗体
英文名称: MFGE8/BA46
抗体货号: YB--6454R
产品规格: 20ul/50ul/100ul/200ul
级    别: 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 1580元
抗原: KLH conjugated synthetic peptide derived from human MFGE8/BA46:201-300/387
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Rabbit,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/3/12 11:40:00
详细资料:  实验方法技术资料
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诚信指数:1562点
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-MFGE8/BA46抗体

产品编号 YB-6454R
英文名称 MFGE8/BA46
中文名称 乳腺上皮细胞抗原BA46抗体
别    名 BA46; Breast epithelial antigen BA46; Contains Medin; HMFG; Lactadherin [Precursor]; Lactadherin; Medin; MFG E8; MFG-E8; MFGE8; MFGM; MFGM_HUMAN; Milk fat globule EGF factor 8; Milk fat globule EGF factor 8 protein; Milk fat globule-EGF factor 8; O acetyl disialoganglioside synthase; OAcGD3S; SED1.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 心血管  细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Rabbit, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 5.5/20/40kDa
细胞定位 细胞膜 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MFGE8/BA46:201-300/387 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.

Function:
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Subcellular Location:
Membrane. Secreted.

Tissue Specificity:
Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.

Post-translational modifications:
Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.

Similarity:
Contains 1 EGF-like domain.
Contains 2 F5/8 type C domains.

SWISS:
Q08431

Gene ID:
4240

Database links:

Entrez Gene: 4240 Human

Entrez Gene: 17304 Mouse

Entrez Gene: 25277 Rat

Omim: 602281 Human

SwissProt: Q08431 Human

SwissProt: P21956 Mouse

SwissProt: P70490 Rat

Unigene: 3745 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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