Anti-CRIPT抗体-抗体-抗体-生物在线
Anti-CRIPT抗体

Anti-CRIPT抗体

商家询价

产品名称: Anti-CRIPT抗体

英文名称: CRIPT

产品编号: YB--11021R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-CRIPT抗体

产品编号 YB-11021R
英文名称 CRIPT
中文名称 突触后蛋白CRIPT抗体
别    名 CRIPT; CRIPT_HUMAN; Cysteine rich interactor of PDZ3; Cysteine rich PDZ binding protein; Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3; Cysteine-rich PDZ-binding protein; HSPC139; HSPC139 protein; Hypothetical protein CRIPT; Postsynaptic protein CRIPT.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 神经生物学  信号转导  细胞粘附分子  细胞外基质  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRIPT:21-80/101 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.

Function:
Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.

Subunit:
Interacts with TUBB1. Interacts strongly with the PDZ3 domain of members of the DLG4 family. Associates with microtubules (By similarity). Interacts with DLG4. 

Subcellular Location:
Cytoplasm. Cell junction; synapse. Cell projection; dendritic spine. Colocalizes with DLG4 in asymmetric synapses.

Similarity:
Belongs to the CRIPT family. 

SWISS:
Q9P021 

Gene ID:
9419

Database links:
UniProtKB/Swiss-Prot: Q9P021.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application