Anti-HAPLN2抗体-抗体-抗体-生物在线
Anti-HAPLN2抗体

Anti-HAPLN2抗体

商家询价

产品名称: Anti-HAPLN2抗体

英文名称: HAPLN2

产品编号: YB--11051R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-HAPLN2抗体

产品编号 YB-11051R
英文名称 HAPLN2
中文名称 透明质酸及粘蛋白2抗体
别    名 Brain link protein 1; Bral1; Hapln2; HPLN2_HUMAN; Hyaluronan and proteoglycan link protein 2.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
细胞定位 细胞外基质 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HAPLN2:21-120/340 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.

Function:
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid.

Subcellular Location:
Secreted, extracellular space, extracellular matrix (By similarity). 

Tissue Specificity:
Expressed only in adult brain.

Similarity:
Belongs to the HAPLN family. 
Contains 1 Ig-like V-type (immunoglobulin-like) domain. 
Contains 2 Link domains. 

SWISS:
Q9GZV7 

Gene ID:
60484

Database links:

Entrez Gene: 60484 Human

Entrez Gene: 73940 Mouse

Entrez Gene: 64057 Rat

SwissProt: Q9GZV7 Human

SwissProt: Q9ESM3 Mouse

SwissProt: Q9ESM2 Rat

Unigene: 410719 Human

Unigene: 294467 Mouse

Unigene: 76545 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications