Anti-PCDHB3抗体-抗体-抗体-生物在线
Anti-PCDHB3抗体

Anti-PCDHB3抗体

商家询价

产品名称: Anti-PCDHB3抗体

英文名称: PCDHB3

产品编号: YB--11154R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-PCDHB3抗体

产品编号 YB-11154R
英文名称 PCDHB3
中文名称 原钙粘蛋白β3抗体
别    名 Protocadherin beta 3; PCDH beta3; PCDHB 3; PCDHB3; PCDB3_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  细胞粘附分子  细胞骨架  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHB3:301-400/796 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB3 (Protocadherin beta-3) is a 796 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB3) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB3 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 6 cadherin domains.

SWISS:
Q9Y5E6

Gene ID:
56132

Database links:

Entrez Gene: 56132 Human

UniProtKB/Swiss-Prot: Q9Y5E6.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application