Anti-LIFR Polyclonal Antibody
产品名称: Anti-LIFR Polyclonal Antibody
英文名称: Anti-LIFR Polyclonal Antibody
产品编号: K106613P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2023-08-11T10:26:26
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-LIFR Polyclonal Antibody
品牌:solarbio | 货号:K106613P
英文名称 | Anti-LIFR Polyclonal Antibody |
---|---|
别名 | CD118;LIF-R;SJS2;STWS;SWS |
应用 | WB |
稀释比例 | WB 1:500-2000. |
交叉反应 | Human |
蛋白分子量 | 115kDa |
Gene ID | 3977 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human LIFR |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human LIFR |
Subcellular Locations | Cytoplasm Cell membrane |
Swiss Prot | P42702 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |