锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族3抗体北京博奥森生物技术有限公司

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产品名称: 锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族3抗体
英文名称: Anti-ASB3
抗体货号: bs-7736R
产品规格: 100ul
产品产地: 中国
品牌商标: Bioss
价    格: 1580元
抗原: ASB3
抗原来源: KLH conjugated synthetic peptide derived from huma
抗体来源: Rabbit
适用物种: Human,Mouse,Rat,Dog,Cow,Rabbit,
无conjugate:无
Isotype:IgG
应用范围: IHC-P:1:400-800 IHC-F:1:400-800 IF:1:100-500 ELISA:1:500-1000
更新时间: 2019/3/15 18:18:00
详细资料:  实验方法技术资料
浏览人数:5
诚信指数:1406点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京博奥森生物技术有限公司
地址:
北京市通州区马驹桥镇联东U谷西区四期67号楼
邮编:
101102
电话:
4009019800
传真:
010-58129612
联系人:
博奥森
所在区域:
北京·北京
邮件:
公司展台:

产品详细描述

IHC-P:1:400-800 IHC-F:1:400-800  IF:1:100-500  ELISA:1:500-1000; Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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