膜相关鸟苷酸反转激酶1抗体北京博奥森生物技术有限公司

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产品名称: 膜相关鸟苷酸反转激酶1抗体
英文名称: Anti-MAGI1
抗体货号: bs-11352R
产品规格: 100ul
产品产地: 中国
品牌商标: Bioss
价    格: 1580元
抗原: MAGI1
抗原来源: KLH conjugated synthetic peptide derived from huma
抗体来源: Rabbit
适用物种: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,
无conjugate:无
Isotype:IgG
应用范围: WB:1:500-2000 IHC-P:1:400-800 IHC-F:1:400-800 ICC:1:100-500 IF:1:100-500 ELISA:1:500-1000
更新时间: 2019/4/20 16:11:00
详细资料:  实验方法技术资料
浏览人数:7
诚信指数:1428点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京博奥森生物技术有限公司
地址:
北京市通州区马驹桥镇联东U谷西区四期67号楼
邮编:
101102
电话:
4009019800
传真:
010-58129612
联系人:
所在区域:
北京·北京
邮件:
公司展台:

产品详细描述

WB:1:500-2000 IHC-P:1:400-800 IHC-F:1:400-800 ICC:1:100-500 IF:1:100-500  ELISA:1:500-1000; The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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