低密度脂蛋白受体5样蛋白抗体北京博奥森生物技术有限公司

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性能参数

产品名称: 低密度脂蛋白受体5样蛋白抗体
英文名称: Anti-LRP5L
抗体货号: bs-11590R
产品规格: 100ul
产品产地: 中国
品牌商标: Bioss
价    格: 1580元
抗原: LRP5L
抗原来源: KLH conjugated synthetic peptide derived from huma
抗体来源: Rabbit
适用物种: Human,Mouse,Rat,Chicken,Sheep,
无conjugate:无
Isotype:IgG
应用范围: WB:1:500-2000 IHC-P:1:400-800 IHC-F:1:400-800 ICC:1:100-500 IF:1:100-500 ELISA:1:500-1000
更新时间: 2019/3/15 18:19:00
详细资料:  实验方法技术资料
浏览人数:6
诚信指数:1404点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京博奥森生物技术有限公司
地址:
北京市通州区马驹桥镇联东U谷西区四期67号楼
邮编:
101102
电话:
4009019800
传真:
010-58129612
联系人:
博奥森
所在区域:
北京·北京
邮件:
公司展台:

产品详细描述

WB:1:500-2000 IHC-P:1:400-800 IHC-F:1:400-800 ICC:1:100-500 IF:1:100-500  ELISA:1:500-1000; Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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