Anti-SOX18抗体-抗体-抗体-生物在线
Anti-SOX18抗体

Anti-SOX18抗体

商家询价

产品名称: Anti-SOX18抗体

英文名称: SOX18

产品编号: YB--52231R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-SOX18抗体

产品编号 YB-52231R
英文名称 SOX18
中文名称 转录因子SOX18抗体
别    名 HLTS; SOX 18; Sox-18; SOX18_HUMAN; SRY (sex determining region Y) box 18; SRY box 18; Transcription factor SOX 18; Transcription factor SOX-18.  
规格价格 50ul/1580元 购买    100ul/2680元 购买        大包装/询价
说 明 书 50ul  100ul  
研究领域 发育生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 55A
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human SOX18 protein, around C-terminal 100aa: 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008]

Function:
Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.

Subcellular Location:
Nucleus.

DISEASE:
Defects in SOX18 are the cause of hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) [MIM:607823].

Similarity:
Contains 1 HMG box DNA-binding domain.
Contains 1 Sox C-terminal domain.

SWISS:
P35713

Gene ID:
54345

Database links:

Entrez Gene: 54345 Human

Entrez Gene: 20672 Mouse

Entrez Gene: 311723 Rat

Omim: 601618 Human

SwissProt: P35713 Human

SwissProt: P43680 Mouse

Unigene: 8619 Human

Unigene: 264904 Mouse

Unigene: 22446 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application