Anti-Thrombospondin 2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Thrombospondin 2/FITC Conjugated抗体

Anti-Thrombospondin 2/FITC Conjugated抗体

商家询价

产品名称: Anti-Thrombospondin 2/FITC Conjugated抗体

英文名称: Anti-Thrombospondin 2/FITC

产品编号: YB--7524R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-Thrombospondin 2/FITC Conjugated抗体

产品编号 YB-7524R-FITC
英文名称 Anti-Thrombospondin 2/FITC
中文名称 FITC标记的血小板反应蛋白2/凝血酶敏感蛋白2抗体
别    名 THBS2; Thrombospondin-2; Thrombospondin2; TSP2; TSP2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  心血管  细胞生物  细胞因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 128kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Thrombospondin 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.

Function:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. 

Subunit:
Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen.

Tissue Specificity:
High expression in invertebral disk tissue.

DISEASE:
Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.

Similarity:
Belongs to the thrombospondin family.
Contains 2 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 1 TSP C-terminal (TSPC) domain.
Contains 3 TSP type-1 domains.
Contains 8 TSP type-3 repeats.
Contains 1 VWFC domain.

Database links:

Entrez Gene: 7058 Human

Entrez Gene: 21826 Mouse

Entrez Gene: 292406 Rat

Omim: 188061 Human

SwissProt: P35440 Chicken

SwissProt: Q95116 Cow

SwissProt: P35442 Human

SwissProt: Q03350 Mouse

Unigene: 797 Chicken

Unigene: 5522 Cow

Unigene: 371147 Human

Unigene: 26688 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.