Anti--Myosin 18B/FITC Conjugated抗体-抗体-抗体-生物在线
Anti--Myosin 18B/FITC Conjugated抗体

Anti--Myosin 18B/FITC Conjugated抗体

商家询价

产品名称: Anti--Myosin 18B/FITC Conjugated抗体

英文名称: Anti-Myosin 18B/FITC

产品编号: YB--2965R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti--Myosin 18B/FITC Conjugated抗体

产品编号 YB-2965R-FITC
英文名称 Anti-Myosin 18B/FITC
中文名称 FITC标记的肌球蛋白XVIIIb抗体
别    名 MYO18B; myosin 18B; Unconventional myosin-XVIIIb; BK125H2.1; DKFZp434C2422; DKFZp779C1668; MY18B_HUMAN; MYO18B; myosin XVIIIB.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 282kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Myosin-XVIIIb (1805-1855aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin.Mutations in this gene are associated with lung cancer. 

Function:
May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.

Subunit:
Homodimer. May interact with F actin through the GPA motif (Gly/Pro/Ala-rich).

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.

Tissue Specificity:
Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.

Database links:

Entrez Gene: 84700 Human

Omim: 607295 Human

SwissProt: Q8IUG5 Human

Unigene: 417959 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.