Anti-Calcipressin 2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Calcipressin 2/FITC Conjugated抗体

Anti-Calcipressin 2/FITC Conjugated抗体

商家询价

产品名称: Anti-Calcipressin 2/FITC Conjugated抗体

英文名称: Anti-Calcipressin 2/FITC

产品编号: YB--7028R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-Calcipressin 2/FITC Conjugated抗体

产品编号 YB-7028R-FITC
英文名称 Anti-Calcipressin 2/FITC
中文名称 FITC标记的钙调神经磷酸酶调节蛋白2/唐氏综合征候选区域蛋白1样蛋白2抗体
别    名 DSCR1L1; Calcipressin 2; Calcipressin-2; CSP2; Down syndrome candidate region 1-like 1; Down syndrome critical region gene 1 like 1 protein; MCIP2; Myocyte enriched calcineurin interacting protein 2; Myocyte-enriched calcineurin-interacting protein 2; RCAN2; RCAN2_HUMAN; RCN2; Regulator of calcineurin 2; Thyroid hormone responsive protein ZAKI4; Thyroid hormone-responsive protein ZAKI-4; ZAKI4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  染色质和核信号  神经生物学  信号转导  细胞凋亡  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calcipressin 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events. 

Function:
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

Tissue Specificity:
Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.

Similarity:
Belongs to the RCAN family.

Database links:

Entrez Gene: 10231 Human

Entrez Gene: 53901 Mouse

Entrez Gene: 140666 Rat

Omim: 604876 Human

SwissProt: Q14206 Human

SwissProt: Q9JHG2 Mouse

SwissProt: Q8CH27 Rat

Unigene: 440168 Human

Unigene: 710016 Human

Unigene: 251242 Mouse

Unigene: 24428 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.