Anti-MEOX 2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-MEOX 2/FITC Conjugated抗体

Anti-MEOX 2/FITC Conjugated抗体

商家询价

产品名称： Anti-MEOX 2/FITC Conjugated抗体

英文名称： Anti-MEOX 2/FITC

产品编号： YB--7031R-FITC

产品价格： null

产品产地： 中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:29:50

使用范围： 科研使用

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 Anti-MEOX 2/FITC Conjugated抗体

产品编号 YB-7031R-FITC
英文名称 Anti-MEOX 2/FITC
中文名称 FITC标记的间充质同源盒蛋白2抗体
别    名 GAX; Growth arrest-specific homeobox; Homeobox protein MOX 2; Homeobox protein MOX-2; meox2; MEOX2_HUMAN; Mesenchyme homeobox 2; MOX2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  信号转导  细胞因子  Alzheimer's  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEOX 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Closely related homeobox proteins, MOX-1 and MOX-2, belong to a family of nonclustered, diverged homeobox genes that are expressed in overlapping patterns in the paraxial mesoderm and its derivatives. MOX-1 and MOX-2 function transiently in the formation of mesodermal and mesenchymal derivatives. MOX-1 and MOX-2 are implicated in the early steps of mesoderm formation during gastrulation. In addition, the MOX proteins are also involved in somatic differentiation. Significantly, MOX-1 associates more strongly with Pax-1, whereas MOX-2 preferentially associates with Pax-3. Specifically, expression of MOX-2 (also known as mesenchyme homeobox 2 or GAX), has been shown to be critical in axial skeleton development. MOX-2 is not needed for the migration of myogenic precursors into the limb bud, but it is essential for normal appendicular muscle formation and for the normal regulation of myogenic genes. MOX-2 is expressed in placental tissue. The human MEOX2 gene maps to chromosome 7p21.1 and encodes the MOX-2 protein. Mutations in the gene may be involved in craniofacial and/or skeletal abnormalities.

Function:
Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Subunit:
Interacts with RNF10.

Subcellular Location:
Nucleus.

Tissue Specificity:
Embryo and placenta.

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: P50222.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.