Anti-stabilin1/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-stabilin1/FITC Conjugated抗体
英文名称: Anti-stabilin1/FITC
抗体货号: YB--7510R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human stabilin1
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Cow, Horse,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/4/16 10:48:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-stabilin1/FITC Conjugated抗体

产品编号 YB-7510R-FITC
英文名称 Anti-stabilin1/FITC
中文名称 FITC标记的淋巴管内皮细胞和血管内皮细胞受体1抗体
别    名 CLEVER 1; Common lymphatic endothelial and vascular endothelial receptor 1; Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1; fasciclin egf-like; FEEL 1; FELE 1; FEX1; KIAA0246; MS 1 antigen; STAB1; STAB-1; STAB 1; STAB1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  信号转导  生长因子和***  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 273kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human stabilin1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.

Function:
Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. 

Subunit:
Interacts with CHID1. 

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. 

Similarity:
Contains 16 EGF-like domains. 
Contains 7 FAS1 domains. 
Contains 2 laminin EGF-like domains. 
Contains 1 Link domain.

Database links:

Entrez Gene: 23166 Human

Omim: 608560 Human

SwissProt: Q9NY15 Human

Unigene: 301989 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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