Anti-BNIP1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-BNIP1/FITC Conjugated抗体

Anti-BNIP1/FITC Conjugated抗体

商家询价

产品名称: Anti-BNIP1/FITC Conjugated抗体

英文名称: Anti-BNIP1/FITC

产品编号: YB--6681R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-BNIP1/FITC Conjugated抗体

产品编号 YB-6681R-FITC
英文名称 Anti-BNIP1/FITC
中文名称 FITC标记的Bcl2相互作用蛋白1抗体(转化相关基因8蛋白)
别    名 NIP1; BCL2 adenovirus E1B 19kD interacting protein 1; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BNIP1; sec20; SEC20_HUMAN; SEC20L; Transformation-related gene 8 protein; TRG-8; TRG8; Vesicle transport protein SEC20.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BNIP1/TRG8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.
Tissue specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.

Function:
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy.

Subunit:
Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein. 

Subcellular Location:
Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. 

Tissue Specificity:
Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. 

Post-translational modifications:
'Lys-63'-linked polyubiquitination by RNF185 allows recruiting of autophagy receptor SQSTM1, which simultaneously binds both ubiquitin and LC3 to link ubiquitination and autophagy. 

Similarity:
Belongs to the SEC20 family.

Database links:

Entrez Gene: 662 Human

Entrez Gene: 224630 Mouse

Entrez Gene: 140932 Rat

Omim: 603291 Human

SwissProt: Q12981 Human

SwissProt: Q6QD59 Mouse

SwissProt: Q8VHI8 Rat

Unigene: 145726 Human

Unigene: 21795 Mouse

Unigene: 16757 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications