Anti-GAT1/GABA Transporter 1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-GAT1/GABA Transporter 1/FITC Conjugated抗体

Anti-GAT1/GABA Transporter 1/FITC Conjugated抗体

商家询价

产品名称: Anti-GAT1/GABA Transporter 1/FITC Conjugated抗体

英文名称: Anti-GAT1/GABA Transporter 1/FITC

产品编号: YB--6617R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-GAT1/GABA Transporter 1/FITC Conjugated抗体

产品编号 YB-6617R-FITC
英文名称 Anti-GAT1/GABA Transporter 1/FITC
中文名称 FITC标记的γ氨基丁酸运载蛋白1抗体
别    名 GABATHG; GABATR; GABT 1; GABT1; GAT-1; SLC6A1; Sodium and chloride dependent GABA transporter 1; Solute carrier family 6 (neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Guinea Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABA Transporter 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GABA Transporter 1/GAT1 is a gamma-amino butyric acid (GABA) transporter. After its release from interneurons in the CNS, the major inhibitory neurotransmitter GABA is taken up by GABA transporters (GATs). The predominant neuronal GABA transporter GAT1 is localized in GABAergic axons and nerve terminals, where it is thought to influence GABAergic synaptic transmission by removing GABA from the synaptic cleft.

Function:
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

Subunit:
Interacts with MPP5.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.

Database links:

Entrez Gene: 415960 Chicken

Entrez Gene: 6529 Human

Entrez Gene: 232333 Mouse

Entrez Gene: 79212 Rat

Omim: 137165 Human

SwissProt: P30531 Human

SwissProt: P31648 Mouse

SwissProt: P23978 Rat

Unigene: 443874 Human

Unigene: 5260 Mouse

Unigene: 10035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications