Anti-PCDHA12/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-PCDHA12/FITC Conjugated抗体

Anti-PCDHA12/FITC Conjugated抗体

商家询价

产品名称： Anti-PCDHA12/FITC Conjugated抗体

英文名称： Anti-PCDHA12/FITC

产品编号： YB--5825R-FITC

产品价格： null

产品产地： 中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:29:50

使用范围： 科研使用

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 Anti-PCDHA12/FITC Conjugated抗体

产品编号 YB-5825R-FITC
英文名称 Anti-PCDHA12/FITC
中文名称 FITC标记的原钙粘蛋白12抗体
别    名 PCDH alpha 12; PCDH alpha12; PCDHA12; PCDHA 12; PCDHA-12; Protocadherin alpha 12; PCDAC_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA12
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 6 cadherin domains. 

Database links:

Entrez Gene: 56137 Human

Entrez Gene: 192164 Mouse

Entrez Gene: 116779 Rat

Omim: 606318 Human

SwissProt: Q9UN75 Human

SwissProt: Q91Y18 Mouse

SwissProt: Q767I0 Rat

Unigene: 199343 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications